Colorectal Cancer Care in 2025: Precision Over Protocol

• Liquid Biopsy: Detects cancer earlier via blood-based ctDNA

• BRAF-Mutant CRC Therapy: Dabrafenib + Trametinib shows improved survival

• Microbiota-Immune Axis: Gut bacteria impact immune drug effectiveness

2025 Data Highlight:

“Liquid biopsy improved early CRC detection by 61% compared to colonoscopy alone.”
Source: Gastroenterology & Hepatology Journal, 2025

• Individuals with a family history of CRC

• Patients averse to invasive colonoscopy

• MSI-high or BRAF-mutated colorectal tumors

References:

• Liquid Biopsy in CRC Screening: Clinical Impact in 2025 – G&H Journal

• BRAF-Targeted Combinations in Metastatic CRC – ESMO 2025 Abstracts

• Microbiome-Immunotherapy Axis in CRC – Nature Cancer, 2025